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FISH probes

Fluorescence in-situ hybridization (FISH) is a sensitive and useful tool for detecting small populations of interphase cells with clonal aberrations. Once a clonal aberration is identified by routine karyotyping, FISH probes targeting the same aberration can be used on earlier passages of the cell line to determine whether or not earlier passages are aberration-free.

Because of its high degree of sensitivity, FISH can also be used to screen large numbers of cultures for recurrent chromosome aberrations and can be used to detect recurrent aberrations in cell lines that otherwise appear normal by standard cytogenetics.

Human StemCheck™ FISH probes

The CLG Human StemCheck™ FISH probes provide users with a quick and economic means to assess the occurrence of trisomy within their cultured Stem Cell lines. The StemCheck FISH probes target the 4 most common trisomies (Chr 1,12,17,20) that can arise during the culturing and passaging of embryonic stem cells (ESC) and induced pluripotent stem cell (iPSC) lines. [Learn More]

Gene Specific Probes

Cell Line Genetics offers gene specific FISH probes for rapid determination of gene copy number.[Learn More]

Custom FISH Probes

Can’t find a probe you are looking for? Cell Line Genetics can create one for you. [Contact us for more information]

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