Why use aCGH to characterize your cell lines?
Array Comparative Genomic Hybridization (aCGH) is a high resolution karyotype analysis solution for the detection of unbalanced structural and numerical chromosomal alterations with high-throughput capabilities. Addition of SNPs can also detect polylpoidy, loss of heterozygosity, and uniparental disomy.
CLG offers two different array comparative genomic hybridization arrays to help characterize your cell lines. Cell Line Genetics utilizes Agilent’s Microarray platform.
SurePrint G3 Human CGH Microarray Kit, 8x60K – High-throughput, low cost alternative to karyotyping. Average coverage every 41KB with increased coverage in Refseq genes (33KB)
SurePrint G3 Human Genome CGH+SNP Microarray Kit, 4x180K – High resolution array with SNPs included. Average coverage every 25KB with increased coverage in ISCA regions (5KB)